Reactivities: | Human |
Presku: | AAP59552 |
Size: | 100ug |
Weight: | 58kDa |
Gene: | 5126 |
Format: | Lyophilized powder |
Target: | This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Alternative names: | NEC2; PC2; SPC2 |