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PCDH12 (Human) cDNA (1ug)

PCDH12 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human PCDH12 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PCDH12 polyclonal antibody.
Presku: ANA11055
Size: 1ug
Gene: 51294
Target: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Alternative names: VECAD2; VE-cadherin-2
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