Presku: | AAP51642 |
Size: | 100 ug |
Weight: | 74kDa |
Gene: | 22976 |
Format: | Lyophilized powder |
Target: | PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation. |
Alternative names: | PTIP; TNRC2; CAGF28; CAGF29; PACIP1; PAXIP1L; FLJ41049 |