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PARVB (Human) cDNA (1ug)

PARVB (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human PARVB is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PARVB polyclonal antibody.
Presku: ANA11910
Size: 1ug
Gene: 29780
Target: This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
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