Reactivities: | Human |
Presku: | AAP42883 |
Size: | 100ug |
Weight: | 37kDa |
Gene: | 50855 |
Format: | Lyophilized powder |
Target: | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Alternative names: | PAR-6A; PAR6; PAR6C; PAR6alpha; TAX40; TIP-40 |