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PANK2 (pantothenate kinase 2 ) Blocking Peptide (the C terminal of PANK2)(100ug)

PANK2 (pantothenate kinase 2 ) Blocking Peptide (the C terminal of PANK2)(100ug)

This is a synthetic peptide designed for use in combination with anti-PANK2 Antibody (ARP63793_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP63793

Target

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.

Weight

47kDa

Gene Id

80025

Alternative Names

C20orf48; FLJ17232; HARP; HSS; MGC15053; NBIA1; PKAN

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