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PANK2 (pantothenate kinase 2 ) Blocking Peptide (the C terminal of PANK2)(100ug)

PANK2 (pantothenate kinase 2 ) Blocking Peptide (the C terminal of PANK2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PANK2 Antibody (ARP63793_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63793
Size: 100ug
Weight: 47kDa
Gene: 80025
Format: Lyophilized powder
Target: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
Alternative names: C20orf48; FLJ17232; HARP; HSS; MGC15053; NBIA1; PKAN
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