logo
logo
PALB2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251230

PALB2 Antibody

Partner and localizer of BRCA2 (PALB2) plays a critical role in homologous recombination repair (HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks. PALB2 serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 comple, Xenopus/Amphibian, which is essential for homologous recombination. PALB2 strongly stimulates the DNA strand-invasion activity of RAD51, stabilizes the nucleoprotein filament against a disruptive BRC3-BRC4 polypeptide and helps RAD51 to overcome the suppressive effect of replication protein A (RPA). Defects in PALB2 are the cause of Fanconi anemia complementation group N (FANCN). FANCN is a disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia.

Prices direct from ABBIOTEC

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

251230

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PALB2.

Isotype

Rabbit Ig

Accession

Q86YC2

Additional Info

PALB2; Partner and localizer of BRCA2; FANCN

SUPPLIER INFO

ABBIOTEC

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...