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PAK2 (3B5) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252896

PAK2 (3B5) Antibody

PAK2 (P21-activated kinase 2) is a serine/threonine kinase. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

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SPECIFICATIONS

Catalog Number

252896

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of PAK2 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

P38936

Clonality

3B5

Additional Info

P21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6

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