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Cat no: 251925

PAK-4 Antibody

Serine/threonine-protein kinase PAK 4 (PAK4) activates the JNK pathway. PAK4 plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. PAK4 phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin.

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SPECIFICATIONS

Catalog Number

251925

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Can, Ch/Bird, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PAK4.

Isotype

Rabbit Ig

Accession

O96013

Additional Info

Serine/threonine-protein kinase PAK4; p21-activated kinase 4; PAK-4; PAK4; KIAA1142

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