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PADI4 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250811

PADI4 Antibody

Protein-arginine deiminase type-4 (PADI4) catalyzes the citrullination/deimination of arginine residues of proteins. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. PADI4 is e, Xenopus/Amphibian,pressed in eosinophils and neutrophils but is not e, Xenopus/Amphibian,pressed in peripheral monocytes or lymphocytes. PADI4 is a rheumatoid arthritis susceptibility locus due to its important role in increasing citrullination of proteins in rheumatoid arthritis synovial tissues leading to a break in tolerance to citrullinated peptides processed and presented in the appropriate HLA conte, Xenopus/Amphibian,t.

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SPECIFICATIONS

Catalog Number

250811

Size

0.1 mg

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PADI4.

Isotype

Rabbit Ig

Accession

Q9UM07

Additional Info

PADI4; PAD4; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4; Peptidylarginine deiminase IV; HL-60 PAD; PADI4

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