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PACS1 (phosphofurin acidic cluster sorting protein 1 ) Blocking Peptide (the C terminal of PACS1)(100ug)

PACS1 (phosphofurin acidic cluster sorting protein 1 ) Blocking Peptide (the C terminal of PACS1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-PACS1 Antibody (ARP64806_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64806
Size: 100ug
Weight: 62kDa
Gene: 55690
Format: Lyophilized powder
Target: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
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