Pacific Blue(TM) anti-human CD1c

CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in human. The CD1 molecules are type I glycoprotein with structural similarities to MHC class I and a non-covalent associated with beta2-microglobulin, belonging to Ig superfamily. CD1c is expressed on cortical thymocytes, Langerhans cells, dendritic cells, and a subset of B cells. It has been reported that CD1c is also expressed on mature T cells with tightly regulated manner. The function of CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.

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SPECIFICATIONS

Catalog Number

331508

Size

100 microg

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

L161

Gene Id

911

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

This reagent is developed for immunofluorescent staining for flow cytometric analysis, the suggested use of this reagent is ? 2.0 microg per 106 cells in 100 microl volume or 100 microl of whole blood. It is highly recommended that the reagent be titrated for optimal performance for each application.* Pacific Blue(TM) has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue(TM) conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome. ** Pacific Blue(TM) is a registered trademark of Molecular Probes, Inc. Pacific Blue(TM) dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

R7, M241

Regulatory Status

RUO