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P4HB protein (GST tagged) (Full length) (Human) (100 microg)

P4HB protein (GST tagged) (Full length) (Human) (100 microg)

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AEP10025

Target

P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Weight

85

Gene Id

5034

Alternative Names

PHDB; DSI; GIT; PDI; PDIA1; PO4DB; PO4HB; PROHB; ERBA2L; P4Hbeta

SUPPLIER INFO

Aviva Systems Biology Incorporated

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