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p38 alpha MAPK Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250522

p38 alpha MAPK Antibody

p38 alpha MAPK (Mitogen-activated protein kinase 14; SAPK2A) is activated by environmental stressors,Porcinero-inflammatory cytokines and lipopolysaccharide. In turn it phosphorylates various transcription factors including ELK1 and ATF2 and downstream kinases such as MAPKAPK2 and MAPKAPK5. p38 alpha MAPK is activated at the Thr-, Xenopus/Amphibian,-Tyr motif by the dual specificity kinases MAP2K3,Mouse,AP2K6 and MAP2K4. In addition it can be phosphorylated by ATM or ATR upon DNA damage. It can be inhibited by dual specificity phosphatases such as DUSP1, and its kinase activity inhibited by pyridinyl-imidazole compounds that are cytokine-suppressive anti-inflammatory drugs (CSAID).

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SPECIFICATIONS

Catalog Number

250522

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p38 alpha MAPK.

Isotype

Rabbit IgG

Accession

Q16539

Additional Info

p38 MAPK; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MA, Xenopus/Amphibian,-interacting-protein 2; MAP kinase M, Xenopus/Amphibian,I2; SAPK2A; MAPK14

SUPPLIER INFO

ABBIOTEC

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