Reactivities: | Human |
Presku: | AAP35172 |
Size: | 100ug |
Weight: | 49kDa |
Gene: | 9127 |
Format: | Lyophilized powder |
Target: | The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. |
Alternative names: | MGC129625; P2RX6; P2X6; P2XM |