Presku: | AAP35518 |
Size: | 100 ug |
Weight: | 31kDa |
Gene: | 5027 |
Format: | Lyophilized powder |
Target: | The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. |