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p21 Antibody

p21 Antibody

Cat no: 252156


Supplier: ABBIOTEC
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Cyclin-dependent kinase inhibitor 1 (p21) is an important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. P21 binds to and inhibits cyclin-dependent kinase activity,Porcinereventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. p21 functions in the nuclear localization and assembly of the cyclin D-CDK4 comple, Xenopus/Amphibian, and promotes its kinase activity towards RB1. At higher stoichiometric ratios,Porcine21 inhibits the kinase activity of the cyclin D-CDK4 comple, Xenopus/Amphibian,.
Catalogue number: 252156
Reactivities: Human
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P38936
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p21.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: P21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1;CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6