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P16 (1E1) Antibody

P16 (1E1) Antibody

Cat no: 252703

Supplier: ABBIOTEC
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CDK4I or p16-INK4 (Cyclin-dependent kinase 4 inhibitor A) is a negative regulator of the proliferation of normal cells. It is interacting strongly with CDK4 and CDK6 and by subsequently inhibiting their interaction with cyclins D and retinoblastoma protein phosphorylation. Defects in p16-INK4 are involved in tumor formation in a wide range of tissues. These defects cause cutaneous malignant melanoma 2 (CMM2), familial atypical multiple mole melanoma-pancreatic carcinoma syndrome,Mouse,elanoma-astrocytoma syndrome and Li-Fraumeni syndrome.
Catalogue number: 252703
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 ml
Accession: P42771
Antigen: Purified recombinant fragment of P16 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 1E12E10
Additional info: P16; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase inhibitor A; CDK4I; p16-INK4a; p16INK4A; p16-INK4; multiple tumor suppressor 1; MTS-1; CDKN2A; CDKN2; MTS1
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