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Osteoprotegerin Antibody

Osteoprotegerin Antibody

Cat no: 250800

Supplier: ABBIOTEC
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Osteoprotegerin (OPG) acts as a decoy receptor for RANKL by neutralizing its function in osteoclastogenesis. OPG inhibits osteoclast activation and promotes osteoclast apoptosis in vitro. OPG is up-regulated by increasing calcium concentration and estrogens. Defects in OPG are the cause of juvenile Paget disease, which is characterized by rapid bone remodeling leading to deformities, fractures ans osteopenia.
Catalogue number: 250800
Reactivities: Human, Mouse, Bovine, Porcine, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: O00300
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human osteoprotegerin.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin; Osteoclastogenesis inhibitory factor; TNFRSF11B; OCIF; OPG
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