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Osteoprotegerin Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250800

Osteoprotegerin Antibody

Osteoprotegerin (OPG) acts as a decoy receptor for RANKL by neutralizing its function in osteoclastogenesis. OPG inhibits osteoclast activation and promotes osteoclast apoptosis in vitro. OPG is up-regulated by increasing calcium concentration and estrogens. Defects in OPG are the cause of juvenile Paget disease, which is characterized by rapid bone remodeling leading to deformities, fractures ans osteopenia.

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SPECIFICATIONS

Catalog Number

250800

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human osteoprotegerin.

Isotype

Rabbit Ig

Accession

O00300

Additional Info

Tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin; Osteoclastogenesis inhibitory factor; TNFRSF11B; OCIF; OPG

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