
Supplier:
Aviva Systems Biology IncorporatedOPTN Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
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SPECIFICATIONS
Size
200ug
Presku
APL10583
Target
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Weight
47
Gene Id
10133
Alternative Names
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP
Applications
ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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