Presku: | AAP37740 |
Size: | 100 ug |
Weight: | 54kDa |
Gene: | 9480 |
Format: | Lyophilized powder |
Target: | ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. |
Alternative names: | MGC120377; MGC120378; OC-2; OC2 |