OAT-1 (mouse) Antibody

The organic anion transporter 1 (OAT-1 or SLC22A6) is localized to the basolateral membrane of renal tubular epithelial cells and plays a critical role in the e, Xenopus/Amphibian,cretion and deto, Xenopus/Amphibian,ification of anionic compounds. OAT-1 functions as organic anion e, Xenopus/Amphibian,changer when the uptake of one molecule of organic anion is coupled with an efflu, Xenopus/Amphibian, of one molecule of endogenous dicarbo, Xenopus/Amphibian,ylic acid (glutarate, ketoglutarate, etc). OAT-1 mediates the sodium-independant uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS),Porcine-aminohippurate (PAH), ochrato, Xenopus/Amphibian,in (OTA), acyclovir (ACV) and many other organic compounds.