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Nurr1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250795

Nurr1 Antibody

Nuclear receptors and transcription factors play a role in the development and maintenance of neurons that synthesize the neurotransmitter dopamine. The NURR1 gene encodes a 67-kDa member of the steroid-thyroid hormone-retinoid receptor superfamily. The orphan nuclear receptor NURR1 may function as a general coactivator of gene transcription and transcription factor. Mutations in Nurr1 have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophrenia, and maniac depression. Misregulation of Nurr1 may be associated with rheumatoid arthritis.

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SPECIFICATIONS

Catalog Number

250795

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NURR1.

Isotype

Rabbit Ig

Accession

P43354

Additional Info

Nuclear receptor subfamily 4 group A member 2; Orphan nuclear receptor NURR1; Immediate-early response protein NOT; Transcriptionally-inducible nuclear receptor; NR4A2; NOT; NURR1; TINUR

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