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Numb (numb gene homolog (Drosophila) ) Blocking Peptide (the C terminal of Numb)(100ug)

Numb (numb gene homolog (Drosophila) ) Blocking Peptide (the C terminal of Numb)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Numb Antibody (ARP59433_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP59433
Size: 100ug
Weight: 66kDa
Gene: 18222
Format: Lyophilized powder
Target: Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
Alternative names: m-numb; mnb
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