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Nudt15 (nudix (nucleoside diphosphate linked moiety X)-type motif 15 ) Blocking Peptide (the N terminal of Nudt15)(100ug)

Nudt15 (nudix (nucleoside diphosphate linked moiety X)-type motif 15 ) Blocking Peptide (the N terminal of Nudt15)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Nudt15 Antibody (ARP48830_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP48830
Size: 100ug
Weight: 19kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Nudt15 mediates the hydrolysis of some nucleoside diphosphate derivatives. It can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. Nudt15 may have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
Alternative names: 6530403O17; A730068G11Rik; MTH2
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