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NT5E (1D7) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252906

NT5E (1D7) Antibody

NT5E (CD73 (Cluster of Differentiation 73)) is an ecto-5'-nucleotidase. NT5E catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the e, Xenopus/Amphibian,ternal face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase e, Xenopus/Amphibian,ist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.

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SPECIFICATIONS

Catalog Number

252906

Size

0.1 ml

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of NT5E e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q96B60

Clonality

1D7

Additional Info

eN; NT5; CD73; 5'-nucleotidase, ecto (CD73)

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