Supplier:
Aviva Systems Biology IncorporatedNRAS (neuroblastoma RAS viral (v-ras) oncogene homolog ) Blocking Peptide (the middle region of NRAS)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP63292
Target
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Weight
21kDa
Gene Id
The peptide is characterized by mass spectroscopy
Alternative Names
ALPS4; N-ras; NRAS1; NS6
SUPPLIER INFO
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