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NRAS (neuroblastoma RAS viral (v-ras) oncogene homolog ) Blocking Peptide (the middle region of NRAS)(100ug)

NRAS (neuroblastoma RAS viral (v-ras) oncogene homolog ) Blocking Peptide (the middle region of NRAS)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-NRAS Antibody (ARP63292_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63292
Size: 100ug
Weight: 21kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Alternative names: ALPS4; N-ras; NRAS1; NS6
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