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Nr1h3 (nuclear receptor subfamily 1, group H, member 3 ) Blocking Peptide (the C terminal of Nr1h3)(100ug)

Nr1h3 (nuclear receptor subfamily 1, group H, member 3 ) Blocking Peptide (the C terminal of Nr1h3)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Nr1h3 Antibody (ARP32674_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP32674
Size: 100ug
Weight: 50kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Nr1h3 is an orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Nr1h3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Alternative names: AU018371; LXR; RLD1; Unr1
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