Presku: | AAP38670 |
Size: | 100 ug |
Weight: | 50kDa |
Gene: | 10062 |
Format: | Lyophilized powder |
Target: | Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis. |
Alternative names: | LXR-a; LXRA; RLD-1 |