Reactivities: | Human |
Presku: | AAP56365 |
Size: | 100ug |
Weight: | 47kDa |
Gene: | 4885 |
Format: | Lyophilized powder |
Target: | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. |
Alternative names: | NARP; NP-II; NP2 |