Reactivities: | Mouse |
Presku: | AAP36811 |
Size: | 100ug |
Weight: | 26kDa |
Gene: | 384452 |
Format: | Lyophilized powder |
Target: | Noto is a transcription regulator acting downstream of both FOXA2 and T during notochord development.Noto is required for node morphogenesis.Noto is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate. |
Alternative names: | Flh; MmNot; Not; tc |