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NOTCH3 (Notch homolog 3 (Drosophila)) Blocking Peptide (100ug)

NOTCH3 (Notch homolog 3 (Drosophila)) Blocking Peptide (100ug)

This is a synthetic peptide designed for use in combination with anti-NOTCH3 antibody (Catalogue #: ARP32051_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP32051

Target

NOTCH3 encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Weight

244kDa

Gene Id

4854

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