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Norepinephrine Transporter Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253181

Norepinephrine Transporter Antibody

Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.

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SPECIFICATIONS

Catalog Number

253181

Size

0.1 ml

Applications

WB

Reactivities

Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter.

Isotype

Mouse IgG1

Accession

O55192

Additional Info

Sodium-dependent noradrenaline transporter; Norepinephrine transporter; NET\nSolute carrier family 6 member 2\n

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