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NMDAR2A (Tyr1325) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252560

NMDAR2A (Tyr1325) Antibody

NR2A (Glutamate [NMDA] receptor subunit epsilon-1 or NMDA NR2A) is a glutamate-gated ion channel with high calcium permeability and voltage-dependent sensitivity to magnesium. The NMDA channel is involved in long-term potentiation, an activity-dependent increase in synaptic transmission underlying memory and learning. NMDA NR2A is a heteromer composed of a zeta subunit (GRIN1), an epsilon subunit (GRIN2A, GRIN2Bovine, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). NMDA NR2A activation requires binding of agonist to both types of subunits. Phosphorylation of tyrosine 1325 of the NR2A subunit has been shown to be increased in human brain tissue sections from HIV-infected individuals with encephalitis.

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SPECIFICATIONS

Catalog Number

252560

Size

0.1 ml

Applications

WB

Reactivities

Bov, Rabbit

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Tyr1325 of rat NMDA NR2A.

Isotype

Rabbit IgG

Accession

Q00959

Additional Info

NR2A; Glutamate receptor2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; hNR2A; GRIN2A; NMDA NR2A

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