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NLK (nemo-like kinase) Blocking Peptide (the middle region of NLK)(100ug)

NLK (nemo-like kinase) Blocking Peptide (the middle region of NLK)(100ug)

This is a synthetic peptide designed for use in combination with anti-NLK Antibody(ARP56863_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP56863

Target

NLK has a role in cell fate determination, required for differentiation of bone marrow stromal cells. NLK acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. NLK may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP By similarity.NLK is involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.

Weight

58kDa

Gene Id

51701

Alternative Names

DKFZp761G1211; FLJ21033

SUPPLIER INFO

Aviva Systems Biology Incorporated

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