Supplier:
Aviva Systems Biology IncorporatedNkx3-1 Antibody - middle region (ARP37115_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
ARP37115_P050
Target
Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
Weight
27kDa
Gene Id
18095
Alternative Names
Bax; NKX3.1; NKX3A; Nkx-3.1; bagpipe
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