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NKIRAS1 antibody - N-terminal region (ARP55370_P050)

NKIRAS1 antibody - N-terminal region (ARP55370_P050)

This is a rabbit polyclonal antibody against NKIRAS1. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).

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SPECIFICATIONS

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, ZF/Fish

Format

Lyophilized powder

Presku

ARP55370_P050

Target

NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Weight

22kDa

Gene Id

28512

Alternative Names

KBRAS1; kappaB-Ras1

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