Reactivities: | Human |
Presku: | AAP31262 |
Size: | 100ug |
Weight: | 23kDa |
Gene: | 4801 |
Format: | Lyophilized powder |
Target: | NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. |
Alternative names: | CBF-A; CBF-B; HAP3; NF-YB |