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NFYA (nuclear transcription factor Y, alpha) Blocking Peptide (100ug)

NFYA (nuclear transcription factor Y, alpha) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-NFYA antibody (Catalogue #: ARP31380_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP31380
Size: 100 ug
Weight: 37kDa
Gene: 4800
Format: Lyophilized powder
Target: NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
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