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Nfkbiz (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta) Blocking Peptide (the C terminal of Nfkbiz)(100ug)

Nfkbiz (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta) Blocking Peptide (the C terminal of Nfkbiz)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Nfkbiz Antibody (ARP57676_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Mouse
Presku: AAP57676
Size: 100ug
Weight: 80kDa
Gene: 80859
Format: Lyophilized powder
Target: Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Alternative names: AA408868; INAP; Mail
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