Supplier:
Aviva Systems Biology IncorporatedNfkbiz (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta) Blocking Peptide (the C terminal of Nfkbiz)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Mouse
Format
Lyophilized powder
Presku
AAP57676
Target
Nfkbiz is involved in regulation of NF-kappa-B transcription factor complexes. It inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. It inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. It seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50, Nfkbiz has transcriptional activation activity and, together with NFKB1/p50 and RELA, Nfkbiz is recruited to LCN2 promoters.
Weight
80kDa
Gene Id
80859
Alternative Names
AA408868; INAP; Mail
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