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NFKB p50 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251563

NFKB p50 Antibody

NF-kappa-B p50 subunit (NFKB p50) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B comple, Xenopus/Amphibian,es are held in the cytoplasm in an inactive state comple, Xenopus/Amphibian,ed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, is subsequently degraded thus liberating the active NF-kappa-B comple, Xenopus/Amphibian, which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 comple, Xenopus/Amphibian,es are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3.

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SPECIFICATIONS

Catalog Number

251563

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Ch/Bird, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within human NFKB p50.

Isotype

Rabbit Ig

Accession

P19838

Additional Info

Nuclear factor NF-kappa-B p105/p50 subunit; DNA-binding factor KBF1; EBP-1; NFKB1; Nuclear factor NF-kappa-B p50 subunit; NFKB p105/p50

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