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NFE2 (nuclear factor (erythroid-derived 2), 45kDa) Blocking Peptide (the N terminal of NFE2)(100ug)

NFE2 (nuclear factor (erythroid-derived 2), 45kDa) Blocking Peptide (the N terminal of NFE2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-NFE2 Antibody(ARP31217_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP31217
Size: 100ug
Weight: 41kDa
Gene: 4778
Format: Lyophilized powder
Target: NFE2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. NFE2 binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. NFE2 is requires MAFK or other small MAF proteins for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alternative names: NF-E2; p45
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