Reactivities: | Human |
Presku: | AAP38988 |
Size: | 100ug |
Weight: | 100kDa |
Gene: | 4773 |
Format: | Lyophilized powder |
Target: | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Alternative names: | NFAT1; NFATP |