Supplier:
Aviva Systems Biology IncorporatedNFATC1 Polyclonal Antibody (OABB00616)
that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of
activated T cells DNA-binding transcription complex. The NFATC1 gene is mapped on 18q23. Proteins
belonging to this family of transcription factors play a central role in inducible gene transcription during
immune response. NFATC1 was not detected in brain, liver, or kidney.NFATC1 is an inducible nuclear
component which functions as a major molecular target for the immunosuppressive drugs such as
cyclosporin A. The solution structure of the binary complex formed between the core DNA-binding
domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from
the IL2 promoter. Nfatc1 was expressed exclusively in mouse hair follicle stem cells, and using gainand loss-of-function approaches, and Nfatc1 inhibited stem cell activation.
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SPECIFICATIONS
Size
100ug/vial
Applications
WB
Reactivities
Hum
Format
Lyophilized
Presku
OABB00616
SUPPLIER INFO
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