Reactivities: | Human |
Presku: | AAP39978 |
Size: | 100ug |
Weight: | 100kDa |
Gene: | 4772 |
Format: | Lyophilized powder |
Target: | NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. |
Alternative names: | MGC138448; NF-ATC; NFAT2; NFATc |