Home  >  Products  >  NF-H Antibody
NF-H Antibody

NF-H Antibody

Cat no: 250768


Supplier: ABBIOTEC
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Neurofilament triplet H protein (NF-H) is one of the three intermediate filament proteins (L,Mouse, and H) making up neurofilaments. NF-H is involved in the maintenance of neuronal caliber. NF-H has an important function in mature a, Xenopus/Amphibian,ons that is not subserved by the two smaller NF proteins. Phosphorylation plays a major role in the functioning of the larger neurofilament polypeptides (NF-M and NF-H), the levels of phosphorylation being altered developmentally and coincident wih a change in the neurofilament function. Defects in NF-H are a cause of susceptibility to amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder affecting upper and lower motor neurons resulting in fatal paralysis.
Catalogue number: 250768
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P12036
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NF-H.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Neurofilament heavy polypeptide; NF-H; Neurofilament triplet H protein; 200 kDa neurofilament protein; NEFH; NFH