Supplier:
Aviva Systems Biology IncorporatedNECAB3 (N-terminal EF-hand calcium binding protein 3) Blocking Peptide (the N terminal of NECAB3)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP57669
Target
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Weight
44kDa
Gene Id
63941
Alternative Names
APBA2BP; EFCBP3; NIP1; STIP3; SYTIP2; XB51; dJ63M2.4; dJ63M2.5
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