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NDUFA1 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa ) Blocking Peptide (the N terminal of NDUFA1)(100ug)

NDUFA1 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa ) Blocking Peptide (the N terminal of NDUFA1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-NDUFA1 Antibody (ARP64705_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP64705
Size: 100ug
Weight: 8kDa
Gene: 4694
Format: Lyophilized powder
Target: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Alternative names: CI-MWFE; MWFE; ZNF183
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