Nucleoside diphosphate kinase A (NDP kinase A) plays a role in the synthesis of nucleoside triphosphates other than ATP. NDP kinase A possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' e, Xenopus/Amphibian,onuclease activities. NDP kinase A is involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene e, Xenopus/Amphibian,pression. NDP kinase A is required for neural development including neural patterning and cell fate determination.