Reactivities: | Human |
Presku: | AAP49441 |
Size: | 100ug |
Weight: | 36kDa |
Gene: | 54602 |
Format: | Lyophilized powder |
Target: | NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling. |
Alternative names: | FLJ25842; KIAA1165; N4wbp5a |